Quick verdict: South America is adventure-traveler paradise — Patagonia + Machu Picchu + Iguazu Falls + Amazon + Salar de Uyuni. This guide covers 12+ South American countries.
All countries in South America (with full guides)
Peru
Best months: Apr–Jun · 17–21°C days · dry (ERA5 climate data)
Machu Picchu + Inca + Cusco + Lake Titicaca
Argentina
Best months: Sep–Nov · 13–21°C days · some rain (ERA5 climate data)
Patagonia + Iguazu + Buenos Aires + Mendoza wine
Chile
Best months: Nov–Jan · 14–30°C days · dry (ERA5 climate data)
Patagonia + Atacama + Easter Island + wine
Bolivia
Salar de Uyuni + La Paz + Lake Titicaca
Brazil
Best months: May–Jul · 19–25°C days · some rain (ERA5 climate data)
Rio + Amazon + Iguazu + Salvador + beaches
Colombia
Best months: Jun–Aug · 16–26°C days · rainy (ERA5 climate data)
Cartagena + Medellin + Lost City + coffee region
Ecuador
Best months: Jul–Sep · 7–19°C days · some rain (ERA5 climate data)
Galapagos + Quito + Amazon + Andes
Uruguay
Punta del Este + Colonia + cheap beach
Paraguay
Asuncion + waterfalls + off-beaten
Guyana
Kaieteur Falls + Caribbean culture + jungle
Suriname
Amazon + Dutch colonial + Maroon culture
Venezuela
Angel Falls + Caribbean coast (check current safety)
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Updated 2026. Some links on Packzup are affiliate links.
Popular South America travel guides
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Every South America destination
Complete country and city guides for South America — 13 destinations, each with best time to visit, itineraries, food, where to stay and more.
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Before you go: see whether they speak English in South America and what to wear, check the tap water, sort your mobile data, and find out if it is a cash or card destination.